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Trecator SC (Ethionamide) 250mg: Comprehensive Guide and Online Purchase Information

Introduction:

Trecator SC, containing the active ingredient Ethionamide, is a medication primarily used in the treatment of tuberculosis (TB). Specifically, it is often prescribed as part of a multi-drug regimen when first-line anti-TB drugs are ineffective due to drug resistance or if patients cannot tolerate those medications. This page provides a detailed overview of Trecator SC, its uses, dosage, potential side effects, and how to purchase it safely online.

What is Ethionamide (Trecator SC)?

Ethionamide is a synthetic antimicrobial agent that inhibits the growth of Mycobacterium tuberculosis, the bacteria responsible for TB. It works by interfering with the synthesis of mycolic acids, essential components of the bacterial cell wall. Trecator SC, the brand name for Ethionamide, is available in 250mg tablets. Due to its potential for side effects, Ethionamide is typically reserved for cases where other anti-TB drugs are not suitable.

Indications and Uses:

Trecator SC (Ethionamide) is indicated for the treatment of pulmonary and extrapulmonary tuberculosis. Its primary use is in the following situations:

• Drug-Resistant Tuberculosis (DR-TB): When TB strains are resistant to first-line drugs like isoniazid and rifampicin, Ethionamide becomes a crucial component of the treatment regimen.
• Multi-Drug Resistant Tuberculosis (MDR-TB): In cases of MDR-TB, where resistance exists to at least isoniazid and rifampicin, Ethionamide is almost always included in the treatment plan.
• Intolerance to First-Line Drugs: For patients who experience severe side effects from first-line anti-TB drugs, Ethionamide may be considered as an alternative.

Dosage and Administration:

The dosage of Trecator SC (Ethionamide) varies depending on factors such as the patient's weight, the severity of the infection, and other medications they are taking. It is crucial to follow your doctor's instructions precisely. A typical adult dosage is:

• Adults: Usually, 500mg to 1000mg daily, divided into two or three doses. It's often recommended to start with a lower dose (e.g., 250mg once or twice a day) and gradually increase it to minimize side effects. Maximum daily dose is generally 1000mg.
• Children: The dosage for children is determined by weight and should be prescribed by a pediatrician specializing in infectious diseases.

Important Considerations:

• Take with Food: Taking Trecator SC with food can help reduce gastrointestinal side effects.
• Adherence is Key: Consistent adherence to the prescribed treatment regimen is vital for successful TB treatment and to prevent the development of further drug resistance.
• Do Not Stop Medication: Do not stop taking Trecator SC unless instructed by your doctor, even if you feel better. Prematurely stopping the medication can lead to a relapse of TB and the development of drug resistance.
• Regular Monitoring: Regular blood tests and liver function tests are necessary to monitor for potential side effects during treatment with Ethionamide.

Potential Side Effects:

Ethionamide can cause a range of side effects, some of which can be serious. It's important to be aware of these potential effects and report any concerning symptoms to your doctor immediately. Common side effects include:

• Gastrointestinal: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite.
• Neurological: Peripheral neuropathy (numbness, tingling, or pain in the hands and feet), headache, dizziness, depression, anxiety, psychosis.
• Hepatic: Liver inflammation (hepatitis), which can lead to jaundice (yellowing of the skin and eyes).
• Endocrine: Hypothyroidism (underactive thyroid gland).
• Other: Metallic taste, skin rash.

Serious Side Effects (Seek Immediate Medical Attention):

• Severe abdominal pain
• Yellowing of the skin or eyes
• Dark urine
• Persistent nausea or vomiting
• Severe depression or suicidal thoughts
• Severe peripheral neuropathy

Contraindications:

Trecator SC (Ethionamide) is contraindicated in patients with:

• Severe liver disease.
• Hypersensitivity to Ethionamide.

Drug Interactions:

Ethionamide can interact with other medications, potentially altering their effects or increasing the risk of side effects. Inform your doctor about all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some notable drug interactions include:

• Cycloserine: Increased risk of neurological side effects.
• Isoniazid: Increased risk of liver toxicity.
• Alcohol: Increased risk of liver toxicity and neurological side effects.

Pregnancy and Breastfeeding:

Ethionamide should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. It is not recommended for use during breastfeeding, as it can pass into breast milk and may harm the infant. Consult your doctor for advice.

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Table: Trecator SC (Ethionamide) 250mg - Key Information

Feature	Description
Active Ingredient	Ethionamide
Brand Name	Trecator SC
Dosage Form	Tablet
Strength	250mg
Therapeutic Class	Anti-tuberculosis agent
Indications	Drug-resistant TB, MDR-TB, Intolerance to first-line TB drugs
Common Side Effects	Nausea, vomiting, diarrhea, abdominal pain, peripheral neuropathy
Serious Side Effects	Liver inflammation, severe depression, suicidal thoughts, severe peripheral neuropathy
Contraindications	Severe liver disease, hypersensitivity to Ethionamide
Administration	With food to reduce gastrointestinal side effects
Monitoring	Regular blood tests and liver function tests

Table: Ethionamide vs. Other Anti-TB Drugs

Drug	First-Line/Second-Line	Common Side Effects
Isoniazid	First-Line	Liver inflammation, peripheral neuropathy
Rifampicin	First-Line	Liver inflammation, orange discoloration of bodily fluids
Pyrazinamide	First-Line	Liver inflammation, gout, joint pain
Ethambutol	First-Line	Optic neuritis (vision problems)
Ethionamide	Second-Line	Nausea, vomiting, diarrhea, abdominal pain, peripheral neuropathy, liver inflammation
Streptomycin	First-Line/Second-Line	Hearing loss, kidney damage

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Frequently Asked Questions (FAQ):

• What if I miss a dose of Trecator SC?

  • Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• How long will I need to take Trecator SC?

  • The duration of treatment with Trecator SC depends on the severity of your TB infection and your response to treatment. Your doctor will determine the appropriate length of treatment. Typically, treatment for drug-resistant TB lasts for several months, even up to two years.

• Can I drink alcohol while taking Trecator SC?

  • No, it is strongly advised to avoid alcohol while taking Trecator SC, as alcohol can increase the risk of liver damage and worsen neurological side effects.

• How should I store Trecator SC?

  • Store Trecator SC at room temperature, away from heat, moisture, and direct sunlight. Keep out of reach of children.

• Are there any dietary restrictions while taking Trecator SC?

  • It is generally recommended to maintain a healthy and balanced diet while taking Trecator SC. Taking the medication with food can help reduce gastrointestinal side effects. Your doctor may also recommend specific dietary changes based on your individual needs.

• What should I do if I experience severe side effects?

  • If you experience severe side effects, such as severe abdominal pain, yellowing of the skin or eyes, dark urine, persistent nausea or vomiting, severe depression or suicidal thoughts, or severe peripheral neuropathy, seek immediate medical attention.

Disclaimer:

This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. The information provided here should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. We are not responsible for any adverse effects or consequences resulting from the use of any information provided on this page. This medication should only be used under the guidance and supervision of a qualified healthcare professional.

Product Details

Trade Name	Trecator SC
Active Ingredient	Ethionamide
Dosages	250 mg
Category	Other